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[Recombinant] in vivo Recombinant Antibodies

관리자 2023-04-20 Views 1,846

in vivo Recombinant Antibodies

Bio X Cell’s recombinantly manufactured antibodies overcome the limitations of traditionally manufactured antibodies, including genetic drift, gene loss, and gene mutations which can lead to slight changes in binding specificity and antibody affinity over time. This ensures extremely high lot-to-lot consistency and data reproducibility from experiment to experiment.

Our recombinant antibodies are provided as chimeric antibodies with mouse or human IgG constant regions instead of the typical rat or hamster constant regions. This means improved in vivo activity and reduced immunogenicity in mouse and humanized mouse models.

in vivo Recombinant AntibodiesDescription
RecombiMAb™


Recombinant monoclonal antibodies—validated for binding and screened for murine pathogens and protein aggregation. Effectively reduce immunogenicity in mouse models or humanized mouse models.

RecombiMAb™ Isotype ControlsRecombinant isotype control antibodies— offered in multiple species, isotypes, and Fc domain silencing mutations.
InVivoSIM™

High-quality biosimilar antibodies — study the biological effects of a drug without the need to source an expensive pharmaceutical grade therapeutic.

Cat No.

Product Name

Isotype

CP127

RecombiMAb anti-mouse CD4

Mouse IgG2b, Κ

CP128

RecombiMAb anti-mouse CD8α

Mouse IgG2b, Κ

CP146

RecombiMAb anti-mouse CTLA-4 (CD152)

Mouse IgG1, Κ

CP147

RecombiMAb human IgG4 (S228P) isotype control, anti-hen egg lysozyme

Human IgG4, Κ

CP148

RecombiMAb human IgG4 S228P L235E P329G (SPLEPG) isotype control, anti-hen egg lysozyme

Human IgG4

CP149

RecombiMAb human IgG1 (LALA-PG) isotype control, anti-hen egg lysozyme

Human IgG1

CP150

RecombiMAb mouse IgG2a (D265A) isotype control, anti-hen egg lysozyme

Mouse IgG2a

CP151

RecombiMAb anti-mouse PD-1 (CD279) (D265A)

Mouse IgG2a, Κ

CP152

RecombiMAb human IgG4 (S228P) isotype control, anti-respiratory syncytial virus

Human IgG4, Κ

CP153

RecombiMAb anti-mouse PD-1 (CD279) (LALA-PG)

Mouse IgG2a, Κ

CP157

RecombiMAb anti-mouse PD-1 (CD279)

Mouse IgG2a, Κ

CP159

RecombiMAb anti-mouse PD-1 (CD279)

Mouse IgG2a, Κ

CP160

RecombiMAb mouse IgG2a isotype control, unknown specificity

Mouse IgG2a

CP161

RecombiMAb human IgG1 (LALA-PG) isotype control, anti-respiratory syncytial virus

Human IgG1

CP162

RecombiMAb anti-mouse PD-1 (CD279)

Mouse IgG1, Κ

CP168

RecombiMAb anti-mouse PD-L1 (B7-H1)




 

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