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[#BE0327]InVivoMAb anti-human IL-9

관리자 2020-03-12 Views 1,606

About InVivoMAb anti-human IL-9

The MH9A4 monoclonal antibody reacts with human IL-9, a pleiotropic cytokine expressed by Th9 cells, Th2 cells, Th17 cells, regulatory T cells, NKT cells, ILC2s, and mast cells. IL-9 promotes mast cell and T cell proliferation, stimulates mast cell accumulation in tissues, promotes ILC survival, enhances class-switching to IgE in B cells and alters haematopoietic progenitor cell activity. Additionally, IL-9 enhances mucus production from airway epithelial cells and alters barrier function in the intestines. IL-9 is thought to contribute to asthma. The MH9A4 antibody does not block the binding of IL-9 to the IL-9 receptor.

InVivoMAb anti-human IL-9 Specifications

Isotype

Mouse IgG2b, κ

Recommended Isotype Control(s)InVivoMAb mouse IgG2b isotype control, unknown specificity(BE0086)
Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Human IL-9 coupled to ovalbumin

Reported Applications
  • Flow cytometry
  • ELISA
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein A

Molecular Weight

150 kDa

RRID

AB_2819054

Storage

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.


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