InVivoMab anti-mouse IL-7Rα (CD127)

Clone A7R34
Catalog # BE0065
Category InVivoMab Antibodies
Price
Size Regular Price
1 mg $ 150.00
5 mg $ 550.00
25 mg $ 1,840.00
50 mg $ 2,770.00
100 mg $ 3,920.00
About InVivoMab anti-mouse IL-7Rα (CD127)

The A7R34 monoclonal antibody reacts with mouse IL-7Rα also known as CD127. IL-7Rα is a 60-90 kDa type I transmembrane glycoprotein expressed on immature B cells, thymocytes, peripheral T cells, and bone marrow stromal cells. IL-7Rα forms a heterodimer with the common γ chain (γc or CD132) and upon ligation of IL-7 plays important roles in T and B cell development, and T cell homeostasis. Thymic Stromal Lymphopoietin (TSLP) also binds to IL-7Rα as a complex with the TSLPR chain to trigger activation of dendritic cells, and is also involved in B cell development, allergy and autoimmunity. The A7R34 antibody has been shown to block IL-7Rα signaling when administered in vivo.

InVivoMab anti-mouse IL-7Rα (CD127) Specifications
IsotypeRat IgG2a, κ
ImmunogenIL-7Rα-IgG1 fusion protein
Reported Applications
  • in vivo blocking of IL-7Rα signaling
  • Flow cytometry
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Sterility0.2 μM filtered
ProductionPurified from tissue culture supernatant in an animal free facility
PurificationProtein G
RRIDAB_1107590
Molecular Weight150 kDa
StorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
Application References