InVivoMAb anti-mouse DKK3

Clone DKK3-4.22
Catalog # BE0385
Category InVivoMab Antibodies
Price
Size Regular Price
1mg $ 159.00
5mg $ 583.00
25mg $ 1,950.00
50mg $ 2,936.00
100mg $ 4,155.00
About InVivoMAb anti-mouse DKK3

The DKK3-4.22 monoclonal antibody reacts with mouse Dickkopf-3 (DKK3), a secreted glycoprotein and member of the Dickkopf family of molecules. DKK3 is expressed by multiple cell types, including neurons, endothelial cells, keratinocytes, and zona glomerulosa cells of the adrenal cortex. DKK3 is a multifunctional protein involved in various cellular processes, including embryonic development, cell differentiation, proliferation, and apoptosis, via the Wnt pathway. DKK-3 has been shown to potentiate Wnt signaling through interactions with the high-affinity, transmembrane co-receptors Kremen-1 and Kremen-2. DKK3 has been implicated in the pathogenesis of a variety of diseases, including cancer, chronic heart failure, and kidney disease. The expression of DKK3 is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. 

InVivoMAb anti-mouse DKK3 Specifications
IsotypeMouse IgG1, κ
Recommended Isotype Control(s)InVivoMAb mouse IgG1 isotype control, unknown specificity
Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer
ImmunogenMouse DKK3-IgG2b fusion protein
Reported Applicationsin vivo DKK3 blocking
in vitro DKK3 blocking
Western blot
Flow cytometry
FormulationPBS, pH 7.0
Contains no stabilizers or preservatives
Endotoxin<2EU/mg (<0.002EU/μg)
Determined by LAL gel clotting assay
Purity>95%
Determined by SDS-PAGE
Sterility0.2 µm filtration
ProductionPurified from tissue culture supernatant in an animal free facility
PurificationProtein G
Molecular Weight150 kDa
StorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
Application References